Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. Common posttranslational modifications include methylation of the ε-amino group, giving methyl-, dimethyl-, and trimethyllysine. The latter occurs in calmodulin. Other posttranslational modifications include acetylation. Collagen contains hydroxylysine which is derived from lysine by lysyl hydroxylase. O-Glycosylation of lysine residues in the endoplasmic reticulum or Golgi apparatus is used to mark certain proteins for secretion from the cell.
Synonyms
Lysinum
Lysine monohydrate
6-ammonio-L-norleucine
L-lys
L-Lysin
Lysine hydrochloride
Lysine acid
(S)-lysine
(S)-α,ε-diaminocaproic acid
L-Lysine
Lysine
Lysine acetate
LYS
Lysina
Lysine dihydrate
L-2,6-Diaminocaproic acid
(S)-2,6-diaminohexanoic acid
Brand Names
Aminosyn II in Dextrose
2.75% Travas. Amino Acid InJ.W.elecw.25%dex
4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose
Vamin 18 Electrolyte-free
Aminosyn-PF 7%
Aminosyn II 7% With 50% Dextrose
4.25%trav. Amino Acid InJ.W.O.elect.5%dext.
Aminosyn Sulfite Free
Aminosyn 3.5% M
Aminosyn II 7% With 10% Dextrose
Aminosyn II 8.5% With 50% Dextrose
Aminosyn II 5% Inj
Aminosyn II with Electrolytes in Dextrose with Calcium
4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
Aminosyn II 8.5% Injection
4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Kabiven
Novamine
Periolimel 2.5% E
Smofkabiven Electrolyte Free
4.25% Amino Acid Injection Without Electrolytes In 20% Dextrose Quickmix
RenAmin
Olimel 4.4%
Primene
Smofkabiven Peripheral
Renamin (amino Acids) Injection
HepatAmine
4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Aminosyn II 7% M In 10% Dextrose(dual Chamber)
Olimel 7.6%
Aminosyn II 8.5% M In 20% Dextrose (dual Chamber)
Quick Mix 2.5% Travasol Aa With Electrolytes With 25% Dextrose Injec
Travasol E
2.75% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn II and Dextrose
Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec
Clinimix E
Olimel 5.7%
Perikabiven
TrophAmine
4.25% Travasol Amino Acid Injection With Electrolytes In 5% Dextrose Quickmix
Aminosyn-PF
Aminosyn II 7% Injection
2.75% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Quickmix
Vamin N
Aminosyn RF
Clinimix
8.5% Freamine III
Nutrineal Pd4
Aminosyn 5%
Travasol
ProcalAmine
5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose
ProSol
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Quickmix
Aminosyn 8.5% Injection With Electrolytes
Premasol - sulfite-free (Amino Acid)
2.5% Travasol Amino Acid Injection Without Electrolytes In 10% Dextrose Quickmix
NephrAmine
Travasol Amino Acid Inj 5.5%
20% Prosol
Olimel 5.7% E
Smofkabiven
4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Primene 10%
5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
2.75%travasol Amino Acid InJ.W.eleC.W.5%dex.
Olimel 7.6% E
Xyzmune
Aminosyn II
FreAmine HBC
Primene 10%-liq IV
Aminosyn-PF 10%
4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose
Aminosyn HF
Aminosyn II 10% With Electrolytes
Essepna
2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Clinimix
Aminosyn 8.5%
Synthamin
Aminosyn II In Dextrose Injection
Aminosyn II with Electrolytes
Travasol Inj Without Electrolytes 5.5%
Plenamine
Nephramine Liq IV
Lysakare
Imubolic
Effervescent Potassium Chloride
Travasol Amino Acid Inj 8.5%
Aminosyn
Smofkabiven Extra Nitrogen Electrolyte Free
FreAmine III
Aminosyn RF Injection
Clinisol
4.25% Travasol Amino Acid Without Electrolytes In 5% Dextrose Quickmix
Travasol Inj Without Electrolytes 8.5%
Aminosyn 7%
Aminosyn 10% W Electrolytes
4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose
2.5%travasol Amino Acid InJ.W.eleC.W.25%dex
Olimel 4.4% E
Olimel 3.3% E
Smofkabiven Extra Nitrogen
Hepatasol
5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose
Indication
Supplemental lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682