ACA

6-AMINOHEXANOIC ACID

Created:	1999-07-08
Last modified:	2024-09-27

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20 entries where ACA is found as a standalone ligand10 entries where ACA is covalently linked to polymer or other heterogen groups 29 entries where ACA is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	22
Chiral Atom Count	0
Bond Count	21
Aromatic Bond Count	0

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Chemical Component Summary
Name	6-AMINOHEXANOIC ACID
Synonyms	AMINOCAPROIC ACID
Systematic Name (OpenEye OEToolkits)	6-aminohexanoic acid
Formula	C₆ H₁₃ N O₂
Molecular Weight	131.173
Type	PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)CCCCCN
SMILES	CACTVS	3.341	NCCCCCC(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
Canonical SMILES	CACTVS	3.341	NCCCCCC(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(CCC(=O)O)CCN
InChI	InChI	1.03	InChI=1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChIKey	InChI	1.03	SLXKOJJOQWFEFD-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00513
Name	Aminocaproic acid
Groups	investigational approved
Description	An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Synonyms	omega-Aminohexanoic acid Epsilon-Aminocaproic acid Epsilon Aminocaproic Acid epsilon-Aminohexanoic acid 6-aminohexanoic acid omega-Aminocaproic acid Epsilcapramine acidum aminocaproicum Acide aminocaproïque Aminocapronsäure Aminocaproic acid EACS Ácido aminocapróico EACA 6-Aminocaproic acid
Brand Names	BAMBOO SALT Eunganggo Jook Yeom Solco Platino Iondenti Tooth Aminocaproic Acid Hea YanToothpaste Mastikis Mastic GumCare Rootsallo Toothpaste Amicar Tab 500mg Solmeet denti doctor Mastikis Gold 28tak Gum Care Tooth Yumaki Original Mint Tooth Amicar - Tab, 500mg Exoden White Tooth LACSIAN new perfect all care tooth Aminocaproic acid BAMBOO SALT Eunganggo Jook Yeom Toothpaste Amicar Syr 250mg/ml Saltrain Tooth Amicar - Syr 250mg/ml Amicar Inj 250mg/ml Amicar Injection - Liq IV 250mg/ml NAVI Black and C-Clinic Relief and Nature Toothpast E Jasmine Mint Gray Salt Tooth Gray Salt Solmeet Greensaltrain Tooth Mastikis Mastic 24K Dr.LORD Green Propol Tooth Clean Breath Tooth Salt Tooth Hae Yan Tooth Amicar Dr.EL GUM CARE TOOTH HiMangChanToothpaste
Indication	For use in the treatment of excessive postoperative bleeding.
Categories	Acids, Acyclic Amino Acids Amino Acids, Peptides, and Proteins Aminocaproates Antifibrinolytic Agents Blood and Blood Forming Organs Caproates Coagulants Decreased Fibrinolysis Fibrin Modulating Agents Hematologic Agents Hemostatics
ATC-Code	B02AA01
CAS number	60-32-2

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Plasminogen	MEHKEVVLLLLLFLKSGQGEPLDDYVNTQGASLFSVTKKQLGAGSIEECA...	unknown	inhibitor
Tissue-type plasminogen activator	MDAMKRGLCCVLLLCGAVFVSPSQEIHARFRRGARSYQVICRDEKTQMIY...	unknown	antagonist
Apolipoprotein(a)	MEHKEVVLLLLLFLKSAAPEQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQ...	unknown	other
Aldehyde oxidase	MDRASELLFYVNGRKVIEKNVDPETMLLPYLRKKLRLTGTKYGCGGGGCG...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
Pharos	CHEMBL1046
PubChem	517030, 564
ChEMBL	CHEMBL1046
ChEBI	CHEBI:79212, CHEBI:16586, CHEBI:57826
CCDC/CSD	ZEMCIG, ZEMCEC, ZEMCAY, ZEMCUS, AMCAPR11, JIZHEF, EZOGAD, JIHFUE, QEGFIR, AMCAPR10, GAHHIK